S Sarkar, KK Zadrozny, R Zadorozhnyi, RW Russell, CM Quinn, A Kleinpeter, S Ablan, C Xu, JR Perilla, EO Freed, BK Ganser-Pornillos, O Pornillos, AM Gronenborn, T Polenova. (2022). Structural basis of HIV-1 maturation inhibitor binding and activity. (bioRxiv)

A Yu, EMY Lee, JAG Briggs, BK Ganser-Pornillos, O Pornillos, GA Voth. (2022). Strain and rupture of HIV-1 capsids during uncoating. Proc Natl Acad Sci USA 119, e2117781119. (Pubmed)

G Xue, K Braczyk, D Gonçalves-Carneiro, DM Dawidziak, K Sanchez, H Ong, Y Wan, KK Zadrozny, BK Ganser-Pornillos, PD Bieniasz, O Pornillos. (2022). Poly(ADP-ribose) potentiates ZAP antiviral activity. PLoS Pathog 18, e1009202. (Pubmed)(PMC8853533)


R Zadorozhnyi, S Sarkar, CM Quinn, KK Zadrozny, BK Ganser-Pornillos, O Pornillos, AM Gronenborn, T Polenova. (2021). Determination of histidine protonation states in proteins by fast magic angle spinning NMR. Front Mol Biosci 8, 767040. (Pubmed)(PMC8703106)

K Zurowska, A Alam, BK Ganser-Pornillos, O Pornillos. (2021). Structural evidence that MOAP1 and PEG10 are derived from retrovirus/retrotransposon Gag proteins. Proteins 90, 309-313. (Pubmed)

MV Buckmaster, KK Zadrozny, BK Ganser-Pornillos, O Pornillos, SP Goff. (2021). Structural determinants of virion assembly and release in the C terminus of the Mason-Pfizer monkey virus capsid protein. J Virol 95, e0061521. (Pubmed)


JE Eschbach, JL Elliott, W Li, KK Zadrozny, K Davis, SJ Mohammed, DQ Lawson, O Pornillos, AN Engelman, SB Kutluay. (2020). Capsid lattice destabilization leads to premature loss of the viral genome and integrase enzyme during HIV-1 infection. J Virol 95, e00984-20. (Pubmed)(PMC7944438)

DE Christensen, BK Ganser-Pornillos, JS Johnson, O Pornillos, WI Sundquist. (2020). Reconstitution and visualization of HIV-1 capsid-dependent replication and integration in vitro. Science 370, eabc8420. (Pubmed)(PMC8022914)

AE Ward, V Kiessling, O Pornillos, JM White, BK Ganser-Pornillos, LK Tamm. (2020). HIV-cell membrane fusion intermediates are restricted by Serincs as revealed by cryo-electron and TIRF microscopy. J Biol Chem 295, 15183-15196. (Pubmed)(PMC7650252)

A Yu, KA Skorupka, AJ Pak, BK Ganser-Pornillos, O Pornillos, GA Voth. (2020). TRIM5α self-assembly and compartmentalization of the HIV-1 viral capsid. Nat Commun 11, 1307. (Pubmed)(PMC7066149)

I Kucharska, P Ding, KK Zadrozny, RA Dick, MF Summers, BK Ganser-Pornillos, O Pornillos. (2020). Biochemical reconstitution of HIV-1 assembly and maturation. J Virol 94, e01844-19. (Pubmed)(PMC7022372)


KA Skorupka, MD Roganowicz, DE Christensen, Y Wan, O Pornillos, BK Ganser-Pornillos. (2019). Hierarchical assembly governs TRIM5α recognition of HIV-1 and retroviral capsids. Sci Adv 5, eaaw3631. (Pubmed)(PMC6881174)(EMD-20562)(EMD-20563)(EMD-20564)(EMD-20565)(EMD-20574)

T Kueck, LM Bloyet, E Cassella, T Zang, F Schmidt, V Brusic, G Tekes, O Pornillos, SPJ Whelan, PD Bieniasz. (2019). Vesicular stomatitis virus transcription is inhibited by TRIM69 in the interferon-induced antiviral state. J Virol 93, e01372-19. (Pubmed)(PMC6880163)

BK Ganser-Pornillos, O Pornillos. (2019). Restriction of HIV-1 and other retroviruses by TRIM5. Nat Rev Microbiol 17, 546-556. (Pubmed)(PMC6858284)

O Pornillos, BK Ganser-Pornillos. (2019). Maturation of retroviruses. Curr Opin Virol 36, 47-55. (Pubmed) (PMC6730672)

M Stevens, B Franke, KA Skorupka, DS Cafiso, O Pornillos, O Mayans, DG Norman. (2019). Exploration of the TRIM fold of MuRF1 using EPR reveals a canonical antiparallel structure, extended COS-box. J Mol Biol 431, 2900-2909. (Pubmed)(PMC6599887)


WI Sundquist, O Pornillos. (2018). Retrovirus restriction by TRIM5α: RINGside at a cage fight. Cell Host Microbe 24, 751-753. (Pubmed) (PMC6464375)

JG Sanchez, KMJ Sparrer, C Chiang, RA Reis, JJ Chiang, MA Zurenski, Y Wan, MU Gack, O Pornillos. (2018) TRIM25 binds RNA to modulate anti-viral defense. J Mol Biol 430, 5280-5293. (Pubmed) (PMC6289755)

RA Dick, KK Zadrozny, C Xu, FKM Schur, TD Lysson, CL Ricana, JM Wagner, JR Perilla, BK Ganser-Pornillos, MC Johnson, O Pornillos, VM Vogt. (2018). Inositol phosphates are assembly co-factors for HIV-1. Nature 560, 509-512. (Pubmed) (PMC6242333) (PDB: 6BHR) (PDB: 6BHS) (PDB: 6BHT)

C Buffone, A Martinez-Lopez, T Fricke, S Opp, M Severgnini, I Cifola, L Petiti, S Frabetti, K Skorupka, KK Zadrozny, BK Ganser-Pornillos, O Pornillos, F Di Nunzio, F Diaz-Griffero. (2018). Nup153 unlocks the nuclear pore complex for HIV-1 nuclear translocation in non-dividing cells. J Virol 92, e00648-18. (Pubmed) (PMC6146805) (PDB: 5TSV) (PDB: 5TSX)

JM Wagner, DE Christensen, A Bhattacharya, DM Dawidziak, MD Roganowicz, Y Wan, RA Pumroy, B Demeler, DN Ivanov, BK Ganser-Pornillos, WI Sundquist, O Pornillos. (2018). General model for retroviral capsid pattern recognition by TRIM5 proteins. J Virol 92, e01563-17. (Pubmed) (PMC5790955) (PDB: 5VA4)


MD Roganowicz, S Komurlu, S Mukherjee, J Plewka, SL Alam, KA Skorupka, Y Wan, D Dawidowski, DS Cafiso, BK Ganser-Pornillos, EM Campbell, O Pornillos. (2017). TRIM5α SPRY/coiled-coil interactions optimize avid retroviral capsid recognition. PLoS Pathog 13, e1006686. (Pubmed) (PMC5667893)

ST Yang, AJB Kreutzberger, V Kiessling, BK Ganser-Pornillos, JM White, LK Tamm. (2017). HIV virions sense plasma membrane heterogeneity for cell entry. Sci Adv 28, e1700338. (Pubmed) (PMC5489272)

KMJ Sparrer, S Gableske, MA Zurenski, ZM Parker, F Full, GJ Baumgart, J Kato, G Pacheco-Rodriguez, C Liang, O Pornillos, J Moss, M Vaughan, MU Gack. (2017). TRIM23 mediates virus-induced autophagy via activation of TBK1. Nat Microbiol 2, 1543-1557. (Pubmed) (PMC5658249)

DM Dawidziak, JG Sanchez, JM Wagner, BK Ganser-Pornillos, O Pornillos. (2017). Structure, catalytic activation of the TRIM23 RING E3 ubiquitin ligase. Proteins 85, 1957-1961. (Pubmed) (PMC5638660) (PDB: 5VZV) (PDB: 5VZW)

PŁ Janczyk, KA Skorupka, JG Tooley, DR Matson, CA Kestner, T West, O Pornillos, PT Stukenberg. (2017). Mechanism of Ska recruitment by Ndc80 complexes to kinetochores. Dev Cell 41, 438-449. (Pubmed) (PMC5926205)


MJ Bayro, BK Ganser-Pornillos, KK Zadrozny, M Yeager, R Tycko. (2016). Helical conformation in the CA-SP1 junction of the immature HIV-1 lattice determined from solid-state NMR of virus-like particles. J Am Chem Soc 138, 12029-12032. (Pubmed) (PMC5636003)

JG Sanchez, JJ Chiang, KM Sparrer, SL Alam, M Chi, MD Roganowicz, B Sankaran, MU Gack, O Pornillos. (2016). Mechanism of TRIM25 catalytic activation in the antiviral RIG-I pathway. Cell Rep 16, 1315-1325. (Pubmed) (PMC5076470) (PDB: 5EYA)

JM Wagner, KK Zadrozny, J Chrustowicz, MD Purdy, M Yeager, BK Ganser-Pornillos, O Pornillos. (2016). Crystal structure of an HIV assembly and maturation switch. eLife 5, e17063. (Pubmed) (PMC4946879) (PDB: 5I4T)

JM Wagner, M Roganowicz, K Skorupka, SL Alam, DE Christensen, GL Doss, Y Wan, GA Frank, BK Ganser-Pornillos, WI Sundquist, O Pornillos. (2016). Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5α. eLife 5, e16309. (Pubmed) (PMC4936894) (PDB: 5EIU) (PDB: 5F7T) (PDB: 5IEA)

Y-L Li, V Chandrasekaran, SD Carter, CL Woodward, D Christensen, KA Dryden, O Pornillos, M Yeager, BK Ganser-Pornillos, GJ Jensen, WI Sundquist. (2016). Primate TRIM5 proteins form hexagonal nets on HIV-1 capsids. eLife 5, e16269. (Pubmed) (PMC4936896)

JM Grime, JF Dama, BK Ganser-Pornillos, CL Woodward, GJ Jensen, M Yeager, GA Voth. (2016). Coarse-grained simulation reveals key features of HIV-1 capsid self-assembly. Nat Commun 7, 11568. (Pubmed) (PMC4869257)


AT Gres, KA Kirby, VN KewalRamani, JJ Tanner, O Pornillos, SG Sarafianos. (2015). X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability. Science 349, 99-103. (Pubmed)


A Bhattacharya, SL Alam, T Fricke, K Zadrozny, J Sedzicki, AB Taylor, B Demeler, O Pornillos, BK Ganser-Pornillos, F Diaz-Griffero, DN Ivanov, M Yeager. (2014). Structural basis of HIV-1 capsid recognition by PF74 and CPSF6. Proc Natl Acad Sci USA 111, 18625-18630. (Pubmed) (PDB: 4QNB)

JG Sanchez, K Okreglicka, V Chandrasekaran, JM Welker, WI Sundquist, O Pornillos. (2014). The tripartite motif coiled-coil is an elongated antiparallel hairpin dimer. Proc Natl Acad Sci USA 111, 2494-2499. (Pubmed) (PDB: 4LTB)


M. Yeager, K. A. Dryden, B. K. Ganser-Pornillos (2013) “Lipid monolayer, sparse matrix screening for growing two-dimensional crystals for electron crystallography: methods, examples,” Methods Mol Biol 955, 527-537 (Pubmed)


BK Ganser-Pornillos, M Yeager, O Pornillos. (2012). Assembly and maturation of HIV. Adv Exp Med Biol 726, 441-465. (Pubmed)


O Pornillos, BK Ganser-Pornillos, M Yeager. (2011). Atomic-level modelling of the HIV capsid. Nature 469, 424-427. (Pubmed) (PDB: 3P05) (PDB: 3P0A)

BK Ganser-Pornillos, V Chandrasekaran, O Pornillos, JG Sodroski, WI Sundquist, M Yeager. (2011). Hexagonal assembly of a restricting Trim5α protein. Proc Natl Acad Sci USA 108, 534-539. (Pubmed)


O Pornillos, BK Ganser-Pornillos, S Banumathi, Y Hua, M Yeager. (2010). Disulfide bond stabilization of the hexameric capsomer of human immunodeficiency virus. J Mol Biol 401, 985-995. (Pubmed) (PDB: 3MGE)

D Zhu, J Hensel, R Hilgraf, M Abbasian, O Pornillos, G Deyanat-Yazdi, XH Hua, S Cox. (2010). Inhibition of protein kinase CK2 expression, activity blocks tumor cell growth in vitro. Mol Cell Biochem 333, 159-167. (Pubmed)


O Pornillos, BK Ganser-Pornillos, BN Kelly, Y Hua, FG Whitby, CD Stout, WI Sundquist, CP Hill, M Yeager. (2009). X-ray structures of the hexameric building block of the HIV capsid. Cell 137, 1282-1292. (Pubmed) (PDB: 3GV2) (PDB: 3H4E) (PDB: 3H47)


BK Ganser-Pornillos, M Yeager, WI Sundquist. (2008). The structural biology of HIV assembly. Curr Opin Struct Biol 18, 203-217. (Pubmed)


Y-J Chen, O Pornillos, S Lieu, C Ma, AP Chen, G Chang. (2007) X-ray structure of EmrE supports dual topology model. Proc Natl Acad Sci USA 104, 18999-19004. (Pubmed) (PDB: 3B5D) (PDB: 3B61) (PDB: 3B62)

BK Ganser-Pornillos, A Cheng, M Yeager. (2007). Structure of full-length HIV-1 CA: a model for the mature capsid lattice. Cell 131, 70-79. (Pubmed) (PDB: 3DIK)

MA Hanson, A Brooun, KA Baker, VP Jaakola, C Roth, EY Chien, A Alexandrov, J Velasquez, L Davis, M Griffith, K Moy, BK Ganser-Pornillos, Y Hua, P Kuhn, S Ellis, M Yeager, RC Stevens. (2007). Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression. Protein Expr Purif 56, 85-92. (Pubmed)

Z Zhang, C Ma, O Pornillos, X Xiu, G Chang, MH Saier Jr. (2007). Functional characterization of the heterooligomeric EbrAB multidrug efflux transporter of Bacillus subtilis. Biochemistry 46, 5218-5225. (Pubmed)


O Pornillos, G Chang. (2006). Inverted repeat domains in membrane proteins. FEBS Lett 580, 358-362. (Pubmed)


O Pornillos, Y-J Chen, AP Chen, G Chang. (2005). X-ray structure of the EmrE multidrug transporter in complex with a substrate. Science 310, 1950-1953. Retraction: G Chang, CB Roth, CL Reyes, O Pornillos, Y-J Chen, AP Chen. (2006). Science 314, 1875.

J Benjamin, BK Ganser-Pornillos, WF Tivol, WI Sundquist, GJ Jensen. (2005). Three-dimensional structure of HIV-1 virus-like particles by electron cryotomography. J Mol Biol 346, 577-588. (Pubmed)


BK Ganser-Pornillos, UK von Schwedler, KM Stray, C Aiken, WI Sundquist. (2004). Assembly properties of the human immunodeficiency virus type 1 CA protein. J Virol 78, 2545-2552. (Pubmed)


O Pornillos, DS Higginson, KM Stray, RD Fisher, JE Garrus, M Payne, HE Wang, SG Morham, WI Sundquist. (2003). HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein. J Cell Biol 162, 425-434. (Pubmed)

BK Ganser, A Cheng, WI Sundquist, M Yeager. (2003). Three-dimensional structure of the M-MuLV CA protein on a lipid monolayer: a general model for retroviral capsid assembly. EMBO J 22, 2886-2892. (Pubmed)

BK Ganser. (2003). Retroviral capsid assembly. PhD Thesis, University of Utah.


O Pornillos, JE Garrus, WI Sundquist. (2002). Mechanisms of enveloped RNA virus budding. Trends Cell Biol 12, 569-579. (Pubmed)

O Pornillos, SL Alam, DR Davis, WI Sundquist. (2002). Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein. Nat Struct Biol 9, 812-817. (Pubmed) (PDB: 1M4P) (PDB: 1M4Q)

O Pornillos. (2002). Ligand interactions of the HIV-1 Gag p6 domain. PhD Thesis, University of Utah.

O Pornillos, SL Alam, RL Rich, DG Myszka, DR Davis, WI Sundquist. (2002). Structure, functional interactions of the Tsg101 UEV domain. EMBO J 21, 2397-2406. (Pubmed) (PDB: 1KPP) (PDB: 1KPQ)


JE Garrus, UK von Schwedler, O Pornillos, SG Morham, KH Zavitz, HE Wang, DA Wettstein, KM Stray, M Côté, RL Rich, DG Myszka, WI Sundquist. (2001). Tsg101, the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell 107, 55-65. (Pubmed)

Y Jenkins, O Pornillos, RL Rich, DG Myszka, WI Sundquist, MH Malim. (2001). Biochemical analyses of the interactions between human immunodeficiency virus type 1 Vpr and p6Gag. J Virol 75, 10537-10542. (Pubmed)


BK Ganser, S Li, VY Klishko, JT Finch, WI Sundquist. (1999). Assembly and analysis of conical models for the HIV-1 core. Science 283, 80-83. (Pubmed)

DB Stierle, AA Stierle, BK Ganser. (1999). Isolation of two highly methylated polyketide derivatives from a yew-associated Penicillium species. J Nat Prod 62, 1147-1150. (Pubmed)


DB Stierle, AA Stierle, B Ganser. (1997). New phomopsolides from a Penicillium sp.  J Nat Prod 60, 1207-1209. (Pubmed)